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Chitosan-Polyoxometalate Nanocomposites: Synthesis, Characterization and Application as Antimicrobial Agents

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Abstract

Polyoxometalates (POMs) were used, together with chitosan (CS), to obtain hybrid nanoaggregates. Three representative POMs were efficiently assembled into nanoparticles of few hundred nm diameter, featuring entangled ribbons substructure. In order to establish suitable preparation and stability conditions, the assemblies were characterized in solution by UV–Vis spectroscopy, dynamic light scattering and ζ-potential. The nanoparticles were tested against E. coli (106 CFU/ml) in aqueous solution, showing a synergic activity of the heteropolyacid H5PMo10V2O40 and CS. For such components, a highly porous and antibacterial film was obtained upon lyophilisation of the colloidal mixture.

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Notes

  1. In the presence of a small amount of CS, Mo 10 V 2 and V 10 gave very broad 51V-NMR signals centred, respectively, at −500 and −550 ppm. The latter value is in agreement with the occurrence of V1–V5 oxo-species [62].

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Acknowledgments

The research leading to these results has received funding from the European Union’s Seventh Framework Programme (FP7/2007–2013) under grant agreement n°246039 and from MIUR (FIRB prot. RBAP11ETKA). We would like to thank the Biotechnology and Bioengineering Application and Research Center staff at the Izmir Institute of Technology for their kind help and technical support. We also thank Dr. Claudio Furlan, CUGAS—University of Padova, for ESEM and EDAX analyses, and Dr. Federico Caicci, Biology Department, University of Padova, for TEM analysis.

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Authors and Affiliations

  1. ITM-CNR and Department of Chemical Sciences, University of Padova, via F. Marzolo 1, 35131, Padua, Italy

    G. Fiorani, O. Saoncella, M. Bonchio & M. Carraro

  2. Department of Chemical Engineering, Izmir Institute of Technology, Gulbahce Kampusu, 35430, Urla, Izmir, Turkey

    P. Kaner & S. A. Altinkaya

  3. ITM-CNR, Via P.Bucci, Cubo 17/C, 87030, Rende, CS, Italy

    A. Figoli

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  1. G. Fiorani
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Correspondence to S. A. Altinkaya or M. Carraro.

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Fiorani, G., Saoncella, O., Kaner, P. et al. Chitosan-Polyoxometalate Nanocomposites: Synthesis, Characterization and Application as Antimicrobial Agents. J Clust Sci 25, 839–854 (2014). https://doi.org/10.1007/s10876-013-0685-x

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