Rhodium catalyzed hydroformylation of 2-phenylsulfonylbicyclo[2.2.1] alkenes: effect of the phenylsulfonyl group

doi:10.1016/j.tetlet.2006.02.041

Tetrahedron Letters

Volume 47, Issue 15, 10 April 2006, Pages 2569-2572

https://doi.org/10.1016/j.tetlet.2006.02.041 Get rights and content

Abstract

The preliminary results of the hydroformylation of 2-phenylsulfonyl substituted norbornene and norbornadiene derivatives catalyzed by the unmodified Rh(CO)₂acac system are presented. The reaction, occurring under standard oxo conditions, gives polyfunctionalized exo norbornene- and exo norbornanecarboxaldehydes. The effect of the phenylsulfonyl group has been evaluated: it has been found that the steric properties of the sulfonyl substituent, more than the electronic ones, influence the regioselectivity of the process.

Graphical abstract

The preliminary results of the hydroformylation of some 2-phenylsulfonylbicyclo[2.2.1] derivatives catalyzed by the unmodified system Rh(CO)₂acac are reported.

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Acknowledgements

This work has been supported by Università Ca’ Foscari di Venezia (ex 60% funds).

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Rhodium catalyzed hydroformylation of 2-phenylsulfonylbicyclo[2.2.1] alkenes: effect of the phenylsulfonyl group

Abstract

Graphical abstract

Section snippets

Acknowledgements

Tetrahedron

Eur. J. Med. Chem.

J. Organomet. Chem.

J. Organomet. Chem.

J. Mol. Cat. A: Chem.

J. Organomet. Chem.

J. Am. Chem. Soc.

J. Organomet. Chem.

Macromolecules