Efficient nitrile hydration mediated by RuII catalysts in micellar media

Alessandra Cavarzan; Alessandro Scarso; Giorgio Strukul

doi:10.1039/B924244A

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Efficient nitrile hydration mediated by Ru^IIcatalysts in micellar media

Alessandra Cavarzan,^a Alessandro Scarso*^a and Giorgio Strukul*^a

Author affiliations

* Corresponding authors

^a Dipartimento di Chimica, Università Ca’ Foscari di Venezia, Dorsoduro 2137, Venezia, Italy
E-mail: alesca@unive.it, strukul@unive.it
Fax: +39-041-2348517
Tel: +39-041-2348569

Abstract

Efficient nitrile hydration to the corresponding amide derivatives is observed in water using poorly soluble [RuCl₂(η⁶-arene)(PR₃)] catalysts 1 with the aid of surfactants to ensure substrate and catalyst solubilization, and enabling ligand effect study on catalytic activity. Amide yields of 40 to 95% can be observed with a variety of aromatic and aliphatic nitriles using the optimized catalyst system, [RuCl₂(p-cymene)(PPh₂OEt)]/Triton X-114. Catalyst separation and recycling is possible.

Download options Please wait...

Article information

DOI: https://doi.org/10.1039/B924244A
Article type: Communication
Submitted: 18 Nov 2009
Accepted: 17 Feb 2010
First published: 16 Mar 2010

Download Citation

Green Chem., 2010,12, 790-794

Permissions

Request permissions

Efficient nitrile hydration mediated by Ru^II catalysts in micellar media

A. Cavarzan, A. Scarso and G. Strukul, Green Chem., 2010, 12, 790 DOI: 10.1039/B924244A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Green Chemistry