SCHEDULED MAINTENANCE
Diasteroselective multi-component assemblies from dynamic covalent imine condensation and metal-coordination chemistry: mechanism and narcissistic stereochemistry self-sorting†
Elena
Badetti, 
a
Nadia Alessandra
Carmo dos Santos,
a
Francesca A.
Scaramuzzo,
a
Carlo
Bravin,
a
Klaus
Wurst,
b
Giulia
Licini
a
and
Cristiano
Zonta
*a
a
Nadia Alessandra
Carmo dos Santos,
a
Francesca A.
Scaramuzzo,
a
Carlo
Bravin,
a
Klaus
Wurst,
b
Giulia
Licini
a
and
Cristiano
Zonta
*a
Abstract
Self-assembly of a modified tris(2-pyridylmethyl)amine TPMA ligand, zinc(II) or cobalt(II) ions, and amino acids have been used effectively as stereo dynamic optical probes for the determination of the enantiomeric excess of free amino acids either using Electronic or Vibrational Circular Dichroism (CD and VCD). Herein, we report the mechanistic and stereochemical study of the self-assembly process which reveals a complex equilibrium in solution where even small variations in the experimental conditions can profoundly affect the final products of the reaction. In particular, variation on the metal stoichiometry switch give rises to an entirely enantio narcissistic self-assembly of the structure.
- This article is part of the themed collections: How does it work? – a collection on mechanistic studies and Editors' collection: Supramolecular Polymers
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