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Synthesis 1991; 1991(11): 1003-1004
DOI: 10.1055/s-1991-26630
DOI: 10.1055/s-1991-26630
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Improved Selectivity in the Chloromethylation of Alkylbenzenes in the Presence of Quaternary Ammonium Salts
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Publication Date:
29 April 2002 (online)
Improved yield and selectivity in the chloromethylation of aromatic hydrocarbons in the presence of several phase transfer catalysts are reported. The best yield (98%) and selectivity (p/o ratio = 8.2) were obtained in the chloromethylation of cumene in the presence of a classical micellar catalyst.